Friday, December 6, 2013

Pharm Notes

Ch 50- Acid Controlling drugs Ant acrids- Neutralize stomach blisterys -Aluminum Salts- constipating effects, a lot apply w/ magnesium to counteract, often used with patients with nephritic distemper (easily excreted) -Magnesium salts- commonly develop diarrhea -Calcium salts- whitethorn drift constipation and kidney stones, desire duration of tart action, -Sodium Bicarbonate- quick onset, scant(p) duration. May cause metabolic alkalosis, sodium content whitethorn cause problems w/ patients w/ HF hypertension get around meds 1-2 hours after antacid Antiflatulents- drugs: Simethicone, Activated Charcoal H2 Antagonists- bowdlerize acid secretion Cimetidine (Tagament)- Binds with P-450, resulting in increased drug levels ranitidine (Zantac) Smoking decreases effectiveness of h2 blockers Proton Pump Inhibitors- achlorhydriaALL stomachal acid secretion is temporarily blocked Used for GERD maintenance therapy, virulent esophagitis, short-term treatmen t of active duodenal and benign stomachic ulcers, Zollinger-Ellison syndrome, manipulation of H. pyloriinduced ulcers. Proton pump inhibitors often work trounce when taken 30 to 60 minutes beforehand meals omeprazole (Prilosec) Pantoprazole (Protonix)- specifically indicated treatment of h pylori, may increase hemorrhage with warfarin.
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other drugs: Sucralfate (Carafate)- forming a protective barrier everywhere ulcers, demo other drugs at least 2 hours before sucralfate, may be used in chronic renal bereavement to reduce phosphate levels Misoprostol (Cytotec)- Used for prevention of NSAID-induc ed gastric ulcers, value gastric mucosa fro! m injury by enhancing topical anaesthetic end product of mucus Ch 51- Bowel Disorder Drugs Antidiarrheals- -Adsorbents: cover walls of GI tract, bind to responsible bacteria or toxin and so eliminated through stool. Examples: bismuth subsalicylate (Pepto-Bismol). change magnitude bleeding time. drear Gums, Tinnitis, hearing loss, dark stools. Decreased engrossment of digoxin, clindamycin, quinidine, hypoglycemic drugs. NO PEPTO BISMOL TO...If you want to get a encompassing essay, order it on our website: OrderCustomPaper.com

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